The monitors are jumping between screens and taking random key hits. It looks like a nasty macro is running.
This generally means that the ETCLink and RFU cables are plugged in reverse order. Both have female 6-Pin Female XLR connectors. On the Expression series the connectors are side by side, and on the Express they are split apart. It is easy to put them in the wrong place in the dark!
Trace the cable back to be sure it is controlling the correct item. Put the cables in the correct location.
Save the show to disk and Deep clear the console. This will clear out the buffers in the processor. Reload the show back in.